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ExoCap™ Kit Optimized for Serum, Plasma and Cell Culture

CORPORATE  06/16/2015
Tokyo, Japan – June 15, 2015 – JSR Corporation (President: Mitsunobu Koshiba), along with its group company, JSR Life Sciences Corporation, today announced the commercial availability of its optimized line of ExoCap™ kits for exosome isolation and enrichment. This new version of ExoCap™ has been designed and optimized for use with serum, plasma and cell culture supernatants with optimized protocols for downstream assays.

Serum or plasma contain a lot of contaminants, consequently it is difficult to isolate exosomes. Our newly developed Treatment Buffer improves the isolation capability of exosomes from these samples.

ExoCap™ are complete kits based on the company's Magnosphere™ magnetic micro beads coated with a JSR Life Sciences proprietary hydrophilic polymer to decrease non-specific binding. Magnosphere™ has been used for automation systems of IVD companies. ExoCap™ kits consists of magnetic beads coupled with antibodies that recognize the exosome surface antigens CD9, CD63, CD81 and EpCAM, Treatment Buffer, Washing/Dilution Buffer, and Exosome Elution Buffer

Exosomes are extracellular vesicles secreted by most cell types and can be found in most biological fluids, including blood, urine, and cultured medium of cell cultures. Exosomes contain various molecular constituents of their cell of origin, including proteins and nucleic acids and is becoming increasingly important as a potential source of biomarkers for health and disease.

"Our new ExoCap™ kits provide a higher level of versatility since they are now optimized to perform well with serum, plasma or cell culture," said Hozumi Sato, Vice President of JSR Corporation. “This breadth of capability is important because exosome isolation and detection of biomarker has the potential to change how we diagnose some of the world’s worst diseases by helping scientists, doctor and researchers identify them much earlier.”

JSR Life Sciences' magnetic bead-based ExoCap™ enables easier processing than ultracentrifugation and cleaner purification than precipitation methods. This ExoCap product offers low non-specific binding, isolation of intact vesicles and target specific purification.
ExoCap™ Kits are available worldwide through JSR Group companies, partners and distributors. Please visit www.jsrlifesciences.com for ordering information.